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Viral diversity and diversification of major non-structural genes vif, vpr, vpu, tat exon 1 and rev exon 1 during primary HIV-1 subtype C infection
(Public Library of Science, http://www.plosone.org/, 2012)
To assess the level of intra-patient diversity and evolution of HIV-1C non-structural genes in primary infection, viral quasispecies obtained by single genome amplification (SGA) at multiple sampling timepoints up to 500 ...
Virtualizing the p-ANAPL library: A step towards drug discovery from African medicinal plants
(Public Library of Science, http://www.plosone.org/, 2014)
Background: Natural products play a key role in drug discovery programs, both serving as drugs and as templates for the synthesis of drugs, even though the quantities and availabilities of samples for screening are often ...
Screening of the pan-African Natural Product Library identifies ixoratannin A-2 and boldine as novel HIV-1 inhibitors
(Public Library of Science, http://www.plosone.org/, 2015)
The continued burden of HIV in resource-limited regions such as parts of sub-Saharan Africa, combined with adverse effects and potential risks of resistance to existing antiretroviral therapies, emphasize the need to ...
Multivariate analysis of Harpagophytum DC. ex Meisn (Pedaliaceae) based on fruit characters
(Academic Journals; http://www.academicjournals.org/ijbc, 2011)
Harpagophytum is bitypic and native to Southern Africa. Its two species are Harpagophytum
procumbens and H. zeyheri. H. procumbens is medicinal. A reliable method of identifying the species is through its fruit. However, ...
The influence of range fire on soil fungi, microbial activity and soil properties along the Boro route of the Okavango Delta
(Global Science Books, http://www.globalsciencebooks.info/, 2011)
The influence of burning on soil microbial dehydrogenase activity, nitrogen content and fungal population along the Boro route in the Okavango Delta was assessed in the flood and dry seasons. Soil samples from the burnt ...
Floristic diversity and uses of medicinal plants sold by street vendors in Gaborone, Botswana
(Global Science Books, http://www.globalsciencebooks.info/, 2011)
The sale of herbal medicine, either as concoctions or single plant specimens, has become common in the streets and main shopping centres of major towns and cities in Botswana. A study was undertaken to collect information ...
Hepatoprotective potentials of water extract of Bauhinia purpurea bark against alcohol induced toxicity
(Academic Journals, http://www.academicjournals.org/SRE, 2011)
Bark of Bauhinia purpurea tree was collected and both the water and methanol extracts were prepared. Both extracts were tested for free radical scavenging activities and phenol content. Water extract was then tested for ...
Isolation of cultivable halophilic Bacillus sp. from the Makgadikgadi Salt Pans in Botswana
(Global Science Books, http://www.globalsciencebooks.info/, 2011)
Halophilic bacteria from the Makgadikgadi salt pans in north central Botswana were isolated using culture-dependent methods. Polymerase chain reaction (PCR) amplification of the 16S rRNA gene and phylogenetic analysis were ...
Ionic and water relations of Sesuvium portulacastrum (L.)
(Academic Journals, http://www.academicjournals.org/, 2010)
The aim of this study was to assess the growth response of Sesuvium portulacastrum (L.) (a halophyte)
to various NaCl concentrations and hence determine how it is adapted to grow optimally under saline
conditions. S. ...
Fungi and their use in the possible control of Nematodes in Botswana soils
(Global Science Books, http://www.globalsciencebooks.info/, 2011)
A study assessing fungi isolated from three climatic regions of Botswana as a possible control for root knot nematodes (Meloidogyne spp.) affecting the tomato(Lycopersicon esculentum L. var. ‘Money maker’) crops was ...