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dc.contributor.authorMolefe-Baikai, O.J.
dc.contributor.authorMooketsi, M.
dc.contributor.authorCainelli, F.
dc.contributor.authorRwegerera, G.M.
dc.date.accessioned2018-11-28T08:57:18Z
dc.date.available2018-11-28T08:57:18Z
dc.date.issued2018-11-12
dc.identifier.citationMolefe-Baikai, O.J. et. al. (2018) The prevalence of microalbuminuria and associated factors among patients with type 2 diabetes mellitus in Botswana. Nigerian Journal of Clinical Practice, Vol. 2, pp. 1430-1437en_US
dc.identifier.issn1119-3077
dc.identifier.urihttp://hdl.handle.net/10311/1869
dc.description.abstractBackground: Microalbuminuria (MA) has been established as an early marker of both diabetic nephropathy and vascular disease in patients with diabetes mellitus (DM). Aims: This study was conducted to determine the prevalence of MA and associated factors among patients with type 2 DM in Botswana. Settings and Design: Outpatient tertiary clinic. Materials and Methods: A cross‑sectional descriptive study involving 289 patients with type 2DM was conducted from January 2013 to June 2013 in Block 6 Reference Clinic, a tertiary clinic in Gaborone, Botswana. A random spot urine sample was collected from each patient with MA defined as urine albumin‑to‑creatinine ratio (ACR) between 3.0 and 30.0 mg/mmol. Statistical Analysis Used: Data analysis was done using STATA version 12 (College Station, TX, USA). Unpaired Student’s t‑test was used for compairing means and Chi‑squared test was used for comparison of proportions between groups. A P value of <0.05 was considered statistically significant. Results: The majority of recruited patients (191, 66.1%) were females, and the median age (interquartile range) of the patients was 52 (42–53) years. The mean glycosylated hemoglobin (HbA1c) for the study population was 8.43% with 70.6% of the population having HbA1c over 7%. MA was found in 129 (44.6%) of study participants. The duration of diabetes of 6–10 years, estimated glomerular filtration rate, HbA1c, and higher serum trigerycides levels were significantly associated with presence of MA. Conclusion: High prevalence of MA raises an urgent need for changes in the management of patients with type 2 DM in Botswana, with emphasis on prevention and reduction of MA to avoid development of overt diabetic nephropathy and ensuing cardiovascular morbidity and mortality.en_US
dc.language.isoenen_US
dc.publisherWolters Kluwer - Medknow; https://wolterskluwer.com/en_US
dc.subjectBotswanaen_US
dc.subjectmicroalbuminuriaen_US
dc.subjectrisk factorsen_US
dc.subjectDiabetes mellitusen_US
dc.titleThe prevalence of microalbuminuria and associated factors among patients with Type 2 diabetes mellitus in Botswanaen_US
dc.typePublished Articleen_US
dc.rights.holderMedical and Dental Consultants Association of Nigeriaen_US
dc.linkhttps://www.researchgate.net/publication/328914092_The_prevalence_of_microalbuminuria_and_associated_factors_among_patients_with_type_2_diabetes_mellitus_in_Botswanaen_US


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