Internal Medicine
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Cerebral venous sinus thrombosis in HIV-infected patients: report of 2 cases
(Pan African Medical Journal; http://www.panafrican-med-journal.com, 2013-09-04)Infection with the human immunodeficiency virus (HIV) is associated with increased risk of cerebrovascular disease; however Cerebral Venous Sinus Thrombosis (CVST) is rarely associated with HIV-related cerebrovascular ... -
Prophylactic antibiotics to prevent surgical site infections in Botswana: findings and implications
(Taylor & Francis, http://www.taylorandfrancis.com, 2018-03-23)Background and aims: Antibiotic prophylaxis in surgery is known to reduce the rate of surgical site infections (SSI) as well as shorten hospital stay. However, there is currently a scarcity of data on antibiotic prophylaxis ... -
Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019: update from the GBD 2019 Study
(Elsevier, www.elsevier.com, 2020-12-11)Cardiovascular diseases (CVDs), principally ischemic heart disease (IHD) and stroke, are the leading cause of global mortality and a major contributor to disability. This paper reviews the magnitude of total CVD ... -
Five insights from the Global Burden of Disease Study 2019
(Elsevier, www.elsevier.com, 2020-10-17)The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system ... -
Antimicrobial utilization research and activities in Botswana, the past, present and the future
(Taylor & Francis, www.tandfonline.com, 2019-09-23)A number of activities are ongoing to reduce AMR in Botswana by improving antimicrobial utilization across all sectors. However, there is a need to share experiences. With the objective of sharing these, the second one ... -
Alanine transaminase and hemoglobin appear to predict the occurrence of antituberculosis medication hepatotoxicity; findings and implications in Botswana
(Taylor & Francis. www.tandfonline.com, 2020-12-01)Objective: Tuberculosis (TB) remains a global health problem, with medications having adverse effects including drug-induced hepatotoxicity. We determined the prevalence of anti-tuberculosis drug-induced hepatotoxicity and ... -
Prevalence and risk Factors for hepatitis B and C among end‑stage renal disease patients on hemodialysis in Gaborone, Botswana
(Medknow Publishers, www.medknow.com, 2021-01)Background: Patients on maintenance hemodialysis (HD) are at risk of blood transmitted infections such as hepatitis B and C. Objectives: To determine the prevalence and risk factors for hepatitis B and hepatitis C virus ... -
Metabolic control and determinants among HIV-infected Type 2 diabetes mellitus patients attending a tertiary llinic in Botswana
(Dove Medical Press Ltd, www.dovepress.com, 2021-01-11)Purpose: We primarily aimed at determining the prevalence of metabolic syndrome and abnormal individual metabolic control variables in HIV-infected participants as compared to HIV-uninfected participants given current ... -
Review of ongoing activities and challenges to improve the care of patients with Type 2 Diabetes across Africa and the implications for the future
(Frontiers Media S.A. www.frontiersin.org, 2020-03-20)Background: There has been an appreciable increase in the number of people in Africa with metabolic syndrome and Type 2 diabetes (T2DM) in recent years as a result of a number of factors. Factors include lifestyle changes, ... -
Response to the novel Corona virus (COVID-19) pandemic across Africa: successes, challenges, and implications for the Future
(Frontiers Media S.A., www.frontiersin.org, 2020-09-11)Background: The COVID-19 pandemic has already claimed considerable lives. There are major concerns in Africa due to existing high prevalence rates for both infectious and non-infectious diseases and limited resources in ... -
Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950-2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019
(Elsevier, 2020-10-17)Background: Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. The Global Burden of Diseases, ... -
Global burden of 87 risk factors in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019
(Elsevier, www.elsevier.com, 2020-10-17)Background: Rigorous analysis of levels and trends in exposure to leading risk factors and quantification of their effect on human health are important to identify where public health is making progress and in which cases ... -
Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
(Elsivier, www.elsevier.com, 2020-02-13)Background: Health system planning requires careful assessment of chronic kidney disease (CKD) epidemiology, but data for morbidity and mortality of this disease are scarce or non-existent in many countries. We estimated ... -
Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
(Elsivier, www.elsivier.com, 2020-08-27)Background: Achieving universal health coverage (UHC) involves all people receiving the health services they need, of high quality, without experiencing financial hardship. Making progress towards UHC is a policy priority ... -
Dolutegravir induced sub-acute hepatic failure in HIV positive treatment naïve man in Botswana
(Sciedu Press, www.sciedupress.com, 2019-09-24)Dolutegravir associated hepatic failure has rarely been reported. Hepatic failure can occur either acutely or after few weeks as it happened in our patient. We report a case of 61 years old HIV-positive treatment naïve ... -
Determinants of comprehensive knowledge of mother to child transmission (MTCT) of HIV and its prevention among Zimbabwean women: Analysis of 2015 Zimbabwe Demographic and Health Survey
(Taylor & Francis; https://www.taylorfrancis.com/, 2019-09-29)Introduction: The global burden of human immunodeficiency virus (HIV) infection/acquired immunodeficiency syndrome has significantly decreased; however, new HIV infections decline slowly; this poses challenges to achieve ... -
Salmonella sepsis and urinary tract infection complicating with acute kidney injury in a HIV positive female patient
(Journal of Clinical and Diagnostic Research; https://www.jcdr.org.in/, 2019-03-01)Urinary Tract Infection (UTI) can rarely be caused by salmonella species. UTI salmonellosis may present as uncomplicated UTI, pyelonephritis or haemorrhagic cystitis. We present a case of a 44-year-old HIV positive female ... -
The prevalence of microalbuminuria and associated factors among patients with Type 2 diabetes mellitus in Botswana
(Wolters Kluwer - Medknow; https://wolterskluwer.com/, 2018-11-12)Background: Microalbuminuria (MA) has been established as an early marker of both diabetic nephropathy and vascular disease in patients with diabetes mellitus (DM). Aims: This study was conducted to determine the prevalence ... -
Short stature and growth hormone deficiency: unexpected manifestations of McCune-Albright syndrome
(BMJ Publishing Group Limited; https://www.bmj.com/, 2018-08-27)McCune-Albright syndrome (MAS) is a rare disease characterised by triad of monostotic or polyostotic fibrous dysplasia, café au-lait skin spots and a variety of endocrine disorders; precocious puberty (PP) being the most ... -
Cavernous sinus thrombosis in a 14-year old boy
(Turkish National Pediatric Society; ipa-world.org/society-resources/code/member-view-news-detail.php?id=446, 2018-07-01)Cavernous sinus thrombosis (CST) is a rare, life-threatening disorder occurring as a result of sepsis or secondary to aseptic causes in the setting of a thrombophilic disorder that has over the years been linked to high ...
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