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dc.contributor.authorOmech, Bernard
dc.contributor.authorTshikuka, Jose-Gaby
dc.contributor.authorMwita, Julius C.
dc.contributor.authorTsima, Billy
dc.contributor.authorNkomazana, Oathokwa
dc.contributor.authorAmone-P’Olak, Kennedy
dc.date.accessioned2016-12-09T11:52:59Z
dc.date.available2016-12-09T11:52:59Z
dc.date.issued2016
dc.identifier.citationOmech, B. et al. (2016) Prevalence and determinants of metabolic syndrome: a cross-sectional survey of general medical outpatient clinics using National Cholesterol Education Program-Adult Treatment Panel III criteria in Botswana. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol. 9, pp. 273–279en_US
dc.identifier.issn1178-7007
dc.identifier.urihttp://hdl.handle.net/10311/1558
dc.description.abstractBackground: Low- and middle-income countries, including Botswana, are facing rising prevalence of obesity and obesity-related cardiometabolic complications. Very little information is known about clustering of cardiovascular risk factors in the outpatient setting during routine visits. We aimed to assess the prevalence and identify the determinants of metabolic syndrome among the general outpatients’ attendances in Botswana. Methods: A cross-sectional study was conducted from August to October 2014 involving outpatients aged ≥20 years without diagnosis of diabetes mellitus. A precoded questionnaire was used to collect data on participants’ sociodemographics, risk factors, and anthropometric indices. Fasting blood samples were drawn and analyzed for glucose and lipid profile. Metabolic syndrome was assessed using National Cholesterol Education Program-Adult Treatment Panel III criteria. Results: In total, 291 participants were analyzed, of whom 216 (74.2%) were females. The mean age of the total population was 50.1 (±11) years. The overall prevalence of metabolic syndrome was 27.1% (n=79), with no significant difference between the sexes (female =29.6%, males =20%, P=0.11). A triad of central obesity, low high-density lipoprotein-cholesterol, and elevated blood pressure constituted the largest proportion (38 [13.1%]) of cases of metabolic syndrome, followed by a combination of low high-density lipoprotein, elevated triglycerides, central obesity, and elevated blood pressure, with 17 (5.8%) cases. Independent determinants of metabolic syndrome were antihypertensive use and increased waist circumference. Conclusion: Metabolic syndrome is highly prevalent in the general medical outpatients clinics. Proactive approaches are needed to screen and manage cases targeting its most important predictors.en_US
dc.language.isoenen_US
dc.publisherDove Medical Press, https://www.dovepress.comen_US
dc.subjectMetabolic syndromeen_US
dc.subjectdeterminantsen_US
dc.subjectgeneral medical outpatient clinicsen_US
dc.subjectBotswanaen_US
dc.titlePrevalence and determinants of metabolic syndrome: a cross-sectional survey of general medical outpatient clinics using National Cholesterol Education Program-Adult Treatment Panel III criteria in Botswanaen_US
dc.typePublished Articleen_US
dc.linkhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008444/pdf/dmso-9-273.pdfen_US


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