Research articles (Dept of Biomedical Sciences)
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Population structure of human gut bacteria in a diverse cohort from rural Tanzania and Botswana
(BMC, https://www.biomedcentral.com/, 2019-01-22)Background: Gut microbiota from individuals in rural, non-industrialized societies differ from those in individuals from industrialized societies. Here, we use 16S rRNA sequencing to survey the gut bacteria of seven ... -
Assessment of prescribing practices at the primary healthcare facilities in Botswana with an emphasis on antibiotics: findings and implications
(Wiley,https://www.wiley.com/en-us, 2017-12-01)Background and Aims: Inappropriate drug prescribing has increased especially in developing countries where systems for monitoring medicine use are not well developed. This increases the rate of antimicrobial resistance. ... -
A step toward timely referral and early diagnosis of cancer: implementation and impact on knowledge of a primary care based training program in Botswana
(Elsevier, www.elsevier.com, 2018-05-29)Health system delays in diagnosis of cancer contribute to the glaring disparities in cancer mortality between high-income countries and low- and middle-income countries. In Botswana, approximately 70% of cancers are diagnosed ... -
Molecular detection of human papillomavirus HPV) in highly fragmented DNA from cervical cancer biopsies using double-nested PCR
(Elsevier, www.elsevier.com, 2018)Archived Formalin-Fixed Paraffin-Embedded (FFPE) tissue specimens can be a valuable source of human papillomavirus (HPV) nucleic acids for molecular biological analyses in retrospective studies. Although successful amplification ... -
Psychoactive substance use among first-year students in a Botswana University: pattern and demographic correlates
(BMC Psychiatry, https://www.biomedcentral.com/about, 2018-08-31)BACKGROUND: Substance use amongst university students is a recognized problem worldwide. Few studies have been carried out in this group in Botswana. These studies have been mostly limited to the use of alcohol and tobacco. ... -
Bilateral loss of vision after spinal anaesthesia on a dwarf patient
(OMICS Internationa, www.omicsonline.org/, 2019-01-04)Achondroplasia is the most common form of dwarfism. Achondroplasia poses multiple anaesthetic challenges ranging from securing intravenous line, monitoring and drug dose calculations and airway management among others. ... -
Cerebral edema during the management of diabetic ketoacidosis in an adult with new onset diabetes mellitus
(Sociedad Cubana de Medicina Intensiva y Emergencias, http://articulos.sld.cu/urgencia/, 2017)Cerebral edema associated with Diabetes Ketoacidosis (DKA) is a rare but frequently fatal complication typically occurring 4 to 12 hours after initiation of treatment, but it can develop any time during DKA management. ... -
Presenting signs of retinoblastoma at a tertiary level teaching hospital in Ethiopia
(African Field Epidemiology Network,http://www.afenet.net/, 2017-09-22)Introduction: Retinoblastoma is a primary malignant intraocular neoplasm that arise from immature retinoblasts with in developing retina. The commonest presenting sign in developing country is proptosis which is the late ... -
A rare case of thymic hyperplasia in a 6-month-old hiv-exposed infant with signs of airway compression
(Medknow publications,http://www.medknow.com/, 2017)This is report of a rare case of thymic hyperplasia in a 6-month-old female child with significant compression effect on the airways and shift of the mediastinum. Timely imaging study and tissue biopsy play an important ... -
A case report of significant congenital depressed skull fracture after cesarean section delivery
(Wolters Kluwer ‑ Medknow,https://wkauthorservices.editage.com/open-access/medknow.html, 2018)We report a case of depressed skull fracture in an hour old newborn delivered by cesarean section for breech presentation. The depression was surgically corrected as a spontaneous resolution did not occur after some interval. ... -
HIV hospital admissions attributable to specific opportunistic infections and factors associated with them at a Botswana Referral Hospital
(Scientific Research, www.scirp.org/, 2015-08-31)Hospital admissions among people living with HIV (PLWH) in Botswana are high. Opportunistic infections (OIs) are responsible for most of these admissions. Although leading OIs causing these admissions have been identified ... -
Availability of guidelines and policy documents for enhancing performance of practitioners at the Primary Health Care (PHC) facilities in Gaborone, Tlokweng and Mogoditshane, Republic of Botswana
(Academic Journals, http://www.academicjournals.org/, 2016-08)This study aimed to determine the profile and availability of policies and guidelines as reference documents at Primary Health Care (PHC) facilities in Gaborone and its surrounding in Botswana using the World Health ... -
A comparative study of the effect of heating on antioxidant potential and lipid profile of rats fed with two vegetable oils-sunflower oil and sesame oil (commonly used in culinary preparation)
(SCIENCEDOMAIN international, 2015-06-04)Aims: Vegetable oils are fats, which are extracted from plant materials especially from seeds, which may change its chemical composition when heated. Therefore the present study investigated the effect of heating of ... -
Does the traditional teaching component of the hybrid curriculum improve the PBL component, in the teaching of anatomy?
(ScopeMed Journal Management System, 2015-04-28)Problem-based learning (PBL) is a relatively new teaching method, which was introduced in many medical schools as an alternative to the traditional method of teaching. At the beginning, the PBL method quickly gained ... -
An in-vivo analysis of the protective effect of the methanol extract of ocimumbasilicum (L.)(MAEOB) on ethanol-induced oxidative stress in albino rats.
(Integrated Journal of British, 2015-09-09)This study was conducted to evaluate the protective effects of graded doses of methanol and aqueousextract of Ocimumbasilicum(L.)(MAEOB) onthe oxidative stress induced by ethanol toxicity. Forty male albino rats of Wister ... -
Staphylococcus aureus nasal colonisation in HIV-infected individuals in Botswana
(2014-08-20)Background: Despite the huge burden of HIV disease, data describing the prevalence of Staphylococcus aureus nasal carriage in the setting of HIV infection in southern Africa are sparse. Objective: This cross-sectional ...