Faculty of Medicine: Recent submissions
Now showing items 21-40 of 102
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Assessment of prescribing practices at the primary healthcare facilities in Botswana with an emphasis on antibiotics: findings and implications
(Wiley,https://www.wiley.com/en-us, 2017-12-01)Background and Aims: Inappropriate drug prescribing has increased especially in developing countries where systems for monitoring medicine use are not well developed. This increases the rate of antimicrobial resistance. ... -
Impact of human immunodeficiency virus infection on survival and acute toxicities from chemoradiation therapy for cervical cancer patients in a limited-resource setting
(Elsevier, https://www.elsevier.com/en-xm, 2018-05-01)Purpose—To prospectively compare survival between human immunodeficiency virus (HIV)-infected versus HIV-uninfected cervical cancer patients who initiated curative chemoradiation therapy (CRT) in a limited-resource ... -
A novel and fatal method of copper sulphate poisoning
(Elsevier, https://www.elsevier.com/, 2014-04)Introduction: Copper sulphate is widely used around the world as a pesticide and seed fungicide. Many cases of accidental intoxication with this substance have been reported among farm workers who have absorbed large amounts ... -
HIV infection: its impact on patients with appendicitis in Botswana
(Springer, https://www.springer.com/gp, 2019-06-11)Background: To compare the presentation, management, and outcome of HIV-positive patients with appendicitis to those of HIV-negative patients with appendicitis. Summary Background Data: The literature is limited regarding ... -
Gynecologic cancer: new and follow-up patient appointments in Botswana during the COVID-19 pandemic
(American Society of Clinical Oncology, https://beta.asco.org/, 2021-04-06)The article presents descriptive data on oncology appointments during COVID-19 lockdown in sub-Saharan Africa. Mobile applications can provide a platform for tracking missed and attended appointments. There was a significant ... -
HIV infection and survival among women with cervical cancer
(American Society of Clinical Oncology, https://beta.asco.org/, 2016-08-29)Purpose Cervical cancer is the leading cause of cancer death among the 20 million women with HIV worldwide. We sought to determine whether HIV infection affected survival in women with invasive cervical cancer. Patients ... -
Explaining disparities in oncology health systems delays and stage at diagnosis between men and women in Botswana: A cohort study
(Public Library of Science, http://www.plosone.org/, 2019-06-06)Purpose Men in Botswana present with more advanced cancer than women, leading to poorer outcomes. We sought to explain sex-specific differences in time to and stage at treatment initiation. Methods Cancer patients who ... -
Botswana's HIV response: policies, context, and future directions
(Wiley, http://onlinelibrary.wiley.com/, 2020-01-17)This brief report describes key periods in the history of the national public health response to the HIV epidemic in Botswana. It reveals the context leading to the development of HIV policies presently in place and current ... -
Factors related to advanced stage of cancer presentation in Botswana
(American Society of Clinical Oncology, https://beta.asco.org/, 2018-12)Purpose: Botswana, a country with a high prevalence of HIV, has an increasing incidence of cancer related mortality in the post–antiretroviral therapy era. Despite universal access to free healthcare, the majority of ... -
Achieving public and global health competencies: a teaching case study of Botswana's cervical cancer screening program
(Wiley, http://onlinelibrary.wiley.com/, 2018-02-18)Objectives: To design and implement a case study on the cervical cancer screening program in Botswana to teach public and global health competencies to undergraduate nursing students. Design and Sample: The case study was ... -
Co-infection with HPV types from the same species provides natural cross-protection from progression to cervical cancer
(BioMed Central (BMC), http://www.infectagentscancer.com/, 2014-08)Background: The worldwide administration of bivalent and quadrivalent HPV vaccines has resulted in cross-protection against non-vaccine HPV types. Infection with multiple HPV types may offer similar cross-protection in the ... -
Availability of WHO essential medicines for cancer treatment in Botswana
(American Society of Clinical Oncology, http://www.asco.org/, 2018-01-23)Purpose Stock outs of cancer drugs are potentially fatal but have not been systematically studied in low- and middle-income countries. The aim of this study was to determine the availability and alignment of the Botswana ... -
HIV infection is not associated with the initiation of curative treatment in women with cervical cancer in Botswana
(Wiley, http://onlinelibrary.wiley.com/, 2019-02-25)BACKGROUND: Cervical cancer is the leading cause of cancer death in Sub-Saharan Africa. The risk of developing cancer is increased for women living with human immunodeficiency virus (HIV) infection. It is unknown which ... -
Assessing nurses’ adherence to the see-and-treat guidelines of Botswana's national cervical cancer prevention programme
(American Association for Cancer Research, https://www.aacr.org/, 2019-12-18)The see-and-treat approach for cervical cancer screening (VIA followed by immediate cryotherapy) was first pilot tested in Botswana in 2009. Botswana’s Ministry of Health and the Botswana-UPenn Partnership collaborated to ... -
Addressing the challenge of p-value and sample size when the significance is borderline: the test of random duplication of participants as a new approach
(Lifescience Global, https://www.lifescienceglobal.com/, 2016)The issue of borderline p-value seems to divide health scientists into two schools of thought. One school of thought argues that when the p-value is greater than or equal to the statistical significance cut-off level of ... -
A mortality review of tuberculosis and HIV co-infected patients in Mahalapye, Botswana: does cotrimoxazole preventive therapy and/or antiretroviral therapy protect against death?
(Aosis/http//aosis.co.za, 2018-11-15)Background: The World Health Organization aims to reduce tuberculosis (TB) mortality rate from 15% in 2015 to 6.5% by 2025. Aim: This study determined the profile of TB and human immunodeficiency virus (HIV) coinfected ... -
A step toward timely referral and early diagnosis of cancer: implementation and impact on knowledge of a primary care based training program in Botswana
(Elsevier, www.elsevier.com, 2018-05-29)Health system delays in diagnosis of cancer contribute to the glaring disparities in cancer mortality between high-income countries and low- and middle-income countries. In Botswana, approximately 70% of cancers are diagnosed ... -
Molecular detection of human papillomavirus HPV) in highly fragmented DNA from cervical cancer biopsies using double-nested PCR
(Elsevier, www.elsevier.com, 2018)Archived Formalin-Fixed Paraffin-Embedded (FFPE) tissue specimens can be a valuable source of human papillomavirus (HPV) nucleic acids for molecular biological analyses in retrospective studies. Although successful amplification ... -
Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019: update from the GBD 2019 Study
(Elsevier, www.elsevier.com, 2020-12-11)Cardiovascular diseases (CVDs), principally ischemic heart disease (IHD) and stroke, are the leading cause of global mortality and a major contributor to disability. This paper reviews the magnitude of total CVD ... -
Five insights from the Global Burden of Disease Study 2019
(Elsevier, www.elsevier.com, 2020-10-17)The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system ...